Cyproheptadine Enhances the I (K) of Mouse Cortical Neurons through Sigma-1 Receptor-Mediated Intracellular Signal Pathway

Cyproheptadine (CPH) is a histamine- and serotonin-receptor antagonist, and its effects are observed recently in the modulation of multiple intracellular signals. In this study, we used cortical neurons and HEK-293 cells transfected with Kv2.1 α-subunit to address whether CPH modify neural voltage-g...

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Detalles Bibliográficos
Autores principales: He, Yan-Lin, Zhang, Chun-Lei, Gao, Xiao-Fei, Yao, Jin-Jing, Hu, Chang-Long, Mei, Yan-Ai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402501/
https://www.ncbi.nlm.nih.gov/pubmed/22844454
http://dx.doi.org/10.1371/journal.pone.0041303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402501/
https://www.ncbi.nlm.nih.gov/pubmed/22844454
http://dx.doi.org/10.1371/journal.pone.0041303

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