Differential Gene Expression in Tamoxifen-Resistant Breast Cancer Cells Revealed by a New Analytical Model of RNA-Seq Data

Resistance to tamoxifen (Tam), a widely used antagonist of the estrogen receptor (ER), is a common obstacle to successful breast cancer treatment. While adjuvant therapy with Tam has been shown to significantly decrease the rate of disease recurrence and mortality, recurrent disease occurs in one th...

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Detalles Bibliográficos
Autores principales: Huber-Keener, Kathryn J., Liu, Xiuping, Wang, Zhong, Wang, Yaqun, Freeman, Willard, Wu, Song, Planas-Silva, Maricarmen D., Ren, Xingcong, Cheng, Yan, Zhang, Yi, Vrana, Kent, Liu, Chang-Gong, Yang, Jin-Ming, Wu, Rongling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402532/
https://www.ncbi.nlm.nih.gov/pubmed/22844461
http://dx.doi.org/10.1371/journal.pone.0041333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402532/
https://www.ncbi.nlm.nih.gov/pubmed/22844461
http://dx.doi.org/10.1371/journal.pone.0041333

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