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SHARPIN is a key regulator of immune and inflammatory responses

Mice with spontaneous mutations in the Sharpin gene develop chronic proliferative dermatitis that is characterized by eosinophilic inflammation of the skin and other organs with increased expression of type 2 cytokines and dysregulated development of lymphoid tissues. The mutant mice share phenotypi...

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Detalles Bibliográficos
Autores principales: Wang, Zhe, Potter, Christopher S, Sundberg, John P, Hogenesch, Harm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402681/
https://www.ncbi.nlm.nih.gov/pubmed/22452937
http://dx.doi.org/10.1111/j.1582-4934.2012.01574.x