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Chinese hamster ovary cell lines selected for resistance to ebolavirus glycoprotein mediated infection are defective for NPC1 expression

Ebolavirus causes severe hemorrhagic fever in humans and non-human primates. Entry of ebolavirus is mediated by the viral glycoprotein, GP; however, the required host factors have not been fully elucidated. A screen utilizing a recombinant Vesicular Stomatitis Virus (VSV) encoding Zaire ebolavirus G...

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Detalles Bibliográficos
Autores principales: Haines, Kathleen M., Vande Burgt, Nathan H., Francica, Joseph R., Kaletsky, Rachel L., Bates, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402687/
https://www.ncbi.nlm.nih.gov/pubmed/22726751
http://dx.doi.org/10.1016/j.virol.2012.05.018