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β1 integrin deletion enhances progression of prostate cancer in the TRAMP mouse model

β1 integrin regulates the response of both normal and cancer cells to their local environment. Although mis-localised in prostate cancer, the role β1 integrin plays in prostate development and carcinogenesis remains unknown. To assess the role of β1 integrin in vivo, we conditionally deleted β1 inte...

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Detalles Bibliográficos
Autores principales: Moran-Jones, Kim, Ledger, Anita, Naylor, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402831/
https://www.ncbi.nlm.nih.gov/pubmed/22829980
http://dx.doi.org/10.1038/srep00526