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Combining automated peak tracking in SAR by NMR with structure-based backbone assignment from (15)N-NOESY
BACKGROUND: Chemical shift mapping is an important technique in NMR-based drug screening for identifying the atoms of a target protein that potentially bind to a drug molecule upon the molecule's introduction in increasing concentrations. The goal is to obtain a mapping of peaks with known resi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402924/ https://www.ncbi.nlm.nih.gov/pubmed/22536902 http://dx.doi.org/10.1186/1471-2105-13-S3-S4 |