New Insights into p53 Signaling and Cancer Cell Response to DNA Damage: Implications for Cancer Therapy

Activation of the p53 signaling pathway by DNA-damaging agents was originally proposed to result either in cell cycle checkpoint activation to promote survival or in apoptotic cell death. This model provided the impetus for numerous studies focusing on the development of p53-based cancer therapies....

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Detalles Bibliográficos
Autores principales: Mirzayans, Razmik, Andrais, Bonnie, Scott, April, Murray, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403320/
https://www.ncbi.nlm.nih.gov/pubmed/22911014
http://dx.doi.org/10.1155/2012/170325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403320/
https://www.ncbi.nlm.nih.gov/pubmed/22911014
http://dx.doi.org/10.1155/2012/170325

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