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Preparation and In Vivo Evaluation of Dichloro(1,2-Diaminocyclohexane)platinum(II)-Loaded Core Cross-Linked Polymer Micelles

The therapeutic performance of oxaliplatin can be improved by incorporating the central cis-dichloro(1,2-diaminocyclohexane)platinum(II) (DACHPt) motif into the core cross-linked block copolymer micelles. We describe here the preparation, cellular uptake, and in vivo evaluation of core cross-linked...

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Detalles Bibliográficos
Autores principales: Oberoi, Hardeep S., Nukolova, Natalia V., Zhao, Yi, Cohen, Samuel M., Kabanov, Alexander V., Bronich, Tatiana K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403332/
https://www.ncbi.nlm.nih.gov/pubmed/22844591
http://dx.doi.org/10.1155/2012/905796