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High precision alignment of cryo-electron subtomograms through gradient-based parallel optimization

BACKGROUND: Cryo-electron tomography emerges as an important component for structural system biology. It not only allows the structural characterization of macromolecular complexes, but also the detection of their cellular localizations in near living conditions. However, the method is hampered by l...

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Detalles Bibliográficos
Autores principales: Xu, Min, Alber, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403359/
https://www.ncbi.nlm.nih.gov/pubmed/23046491
http://dx.doi.org/10.1186/1752-0509-6-S1-S18