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Inhibition of Aldose Reductase by Gentiana lutea Extracts

Accumulation of intracellular sorbitol due to increased aldose reductase (ALR2) activity has been implicated in the development of various secondary complications of diabetes. Thus, ALR2 inhibition could be an effective strategy in the prevention or delay of certain diabetic complications. Gentiana...

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Detalles Bibliográficos
Autores principales: Akileshwari, Chandrasekhar, Muthenna, Puppala, Nastasijević, Branislav, Joksić, Gordana, Petrash, J. Mark, Reddy, Geereddy Bhanuprakash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403369/
https://www.ncbi.nlm.nih.gov/pubmed/22844269
http://dx.doi.org/10.1155/2012/147965