Bioequivalence and Population Pharmacokinetic Modeling of Two Forms of Antibiotic, Cefuroxime Lysine and Cefuroxime Sodium, after Intravenous Infusion in Beagle Dogs

To investigate the bioequivalence and the population pharmacokinetics of cefuroxime lysine and cefuroxime sodium in healthy beagle dogs. A randomized 2-period crossover design in 18 healthy beagle dogs after receiving 20, 40, and 80 mg/kg of cefuroxime lysine or cefuroxime sodium was conducted. A 3-...

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Detalles Bibliográficos
Autores principales: Zhao, Longshan, Li, Qing, Li, Xingang, Yin, Ran, Chen, Xiaohui, Geng, Lulu, Bi, Kaishun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403372/
https://www.ncbi.nlm.nih.gov/pubmed/22911056
http://dx.doi.org/10.1155/2012/507294

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403372/
https://www.ncbi.nlm.nih.gov/pubmed/22911056
http://dx.doi.org/10.1155/2012/507294

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