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Apolipoprotein E: Essential Catalyst of the Alzheimer Amyloid Cascade

The amyloid cascade hypothesis remains a robust model of AD neurodegeneration. However, amyloid deposits contain proteins besides Aβ, such as apolipoprotein E (apoE). Inheritance of the apoE4 allele is the strongest genetic risk factor for late-onset AD. However, there is no consensus on how differe...

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Detalles Bibliográficos
Autores principales:	Potter, Huntington, Wisniewski, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403541/ https://www.ncbi.nlm.nih.gov/pubmed/22844635 http://dx.doi.org/10.1155/2012/489428

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