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A computational procedure for identifying master regulator candidates: a case study on diabetes progression in Goto-Kakizaki rats

BACKGROUND: We have recently identified a number of active regulatory networks involved in diabetes progression in Goto-Kakizaki (GK) rats by network screening. The networks were quite consistent with the previous knowledge of the regulatory relationships between transcription factors (TFs) and thei...

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Detalles Bibliográficos
Autores principales: Piao, Guanying, Saito, Shigeru, Sun, Yidan, Liu, Zhi-Ping, Wang, Yong, Han, Xiao, Wu, Jiarui, Zhou, Huarong, Chen, Luonan, Horimoto, Katsuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403593/
https://www.ncbi.nlm.nih.gov/pubmed/23046543
http://dx.doi.org/10.1186/1752-0509-6-S1-S2