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Development and validation of a prediction index for hand-foot skin reaction in cancer patients receiving sorafenib

BACKGROUND: This study describes a repeated measures prediction index to identify patients at high risk of ≥ grade 2 hand-foot skin reaction (HFSR) before each week of sorafenib therapy. METHODS: Data from 451 patients who received a sorafenib (400 mg bid) as part of a clinical trial were reviewed (...

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Detalles Bibliográficos
Autores principales: Dranitsaris, G., Vincent, M. D., Yu, J., Huang, L., Fang, F., Lacouture, M. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403729/
https://www.ncbi.nlm.nih.gov/pubmed/22228446
http://dx.doi.org/10.1093/annonc/mdr580