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Preeclampsia serum upregulates CD40/CD40L expression and induces apoptosis in human umbilical cord endothelial cells

BACKGROUND: The endothelial cell dysfunction observed in preeclampsia (PE) may be induced by CD40/CD40L signaling. This study investigated the role of CD40/CD40L in the pathogenesis of PE by comparing the effect of maternal serum obtained from healthy pregnant women and PE patients on HUVEC cell gro...

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Detalles Bibliográficos
Autores principales: Wu, Chun-feng, Huang, Fu-dan, Sui, Ren-fang, Sun, Jing-xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403870/
https://www.ncbi.nlm.nih.gov/pubmed/22510585
http://dx.doi.org/10.1186/1477-7827-10-28