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The 1027(th) target candidate in stroke: Will NADPH oxidase hold up?

As recently reviewed, 1026 neuroprotective drug candidates in stroke research have all failed on their road towards validation and clinical translation, reasons being quality issues in preclinical research and publication bias. Quality control guidelines for preclinical stroke studies have now been...

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Detalles Bibliográficos
Autores principales: Radermacher, Kim A, Wingler, Kirstin, Kleikers, Pamela, Altenhöfer, Sebastian, JR Hermans, Johannes, Kleinschnitz, Christoph, HHW Schmidt, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403875/
https://www.ncbi.nlm.nih.gov/pubmed/22625431
http://dx.doi.org/10.1186/2040-7378-4-11