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HTLV-1 modulates the frequency and phenotype of FoxP3(+)CD4(+) T cells in virus-infected individuals

BACKGROUND: HTLV-1 utilizes CD4 T cells as the main host cell and maintains the proviral load via clonal proliferation of infected CD4(+) T cells. Infection of CD4(+) T cells by HTLV-1 is therefore thought to play a pivotal role in HTLV-1-related pathogenicity, including leukemia/lymphoma of CD4(+)...

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Detalles Bibliográficos
Autores principales: Satou, Yorifumi, Utsunomiya, Atae, Tanabe, Junko, Nakagawa, Masanori, Nosaka, Kisato, Matsuoka, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403885/
https://www.ncbi.nlm.nih.gov/pubmed/22647666
http://dx.doi.org/10.1186/1742-4690-9-46