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Detection of identity by descent using next-generation whole genome sequencing data

BACKGROUND: Identity by descent (IBD) has played a fundamental role in the discovery of genetic loci underlying human diseases. Both pedigree-based and population-based linkage analyses rely on estimating recent IBD, and evidence of ancient IBD can be used to detect population structure in genetic a...

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Detalles Bibliográficos
Autores principales: Su, Shu-Yi, Kasberger, Jay, Baranzini, Sergio, Byerley, William, Liao, Wilson, Oksenberg, Jorge, Sherr, Elliott, Jorgenson, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403908/
https://www.ncbi.nlm.nih.gov/pubmed/22672699
http://dx.doi.org/10.1186/1471-2105-13-121