Coexpression of human somatostatin receptor-2 (SSTR2) and SSTR3 modulates antiproliferative signaling and apoptosis

BACKGROUND: Somatostatin (SST) via five G(i) coupled receptors namely SSTR1-5 is known to inhibit cell proliferation by cytostatic and cytotoxic mechanisms. Heterodimerization plays a crucial role in modulating the signal transduction pathways of SSTR subtypes. In the present study, we investigated...

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Detalles Bibliográficos
Autores principales: War, Sajad A, Kumar, Ujendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403965/
https://www.ncbi.nlm.nih.gov/pubmed/22651821
http://dx.doi.org/10.1186/1750-2187-7-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403965/
https://www.ncbi.nlm.nih.gov/pubmed/22651821
http://dx.doi.org/10.1186/1750-2187-7-5

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