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Coexpression of human somatostatin receptor-2 (SSTR2) and SSTR3 modulates antiproliferative signaling and apoptosis

BACKGROUND: Somatostatin (SST) via five G(i) coupled receptors namely SSTR1-5 is known to inhibit cell proliferation by cytostatic and cytotoxic mechanisms. Heterodimerization plays a crucial role in modulating the signal transduction pathways of SSTR subtypes. In the present study, we investigated...

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Detalles Bibliográficos
Autores principales:	War, Sajad A, Kumar, Ujendra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403965/ https://www.ncbi.nlm.nih.gov/pubmed/22651821 http://dx.doi.org/10.1186/1750-2187-7-5

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