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Nef functions in BLT mice to enhance HIV-1 replication and deplete CD4(+)CD8(+) thymocytes
BACKGROUND: The outcome of untreated HIV-1 infection is progression to AIDS and death in nearly all cases. Some important exceptions are the small number of patients infected with HIV-1 deleted for the accessory gene, nef. With these infections, disease progression is entirely suppressed or greatly...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403983/ https://www.ncbi.nlm.nih.gov/pubmed/22640559 http://dx.doi.org/10.1186/1742-4690-9-44 |