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Epigallocatechin-3-gallate suppresses 1-methyl-4-phenyl-pyridine-induced oxidative stress in PC12 cells via the SIRT1/PGC-1α signaling pathway

BACKGROUND: Parkinson’s disease is a high incidence neurodegenerative disease in elderly people, and oxidative stress plays an important role in the pathogenesis. Oxygen metabolism in the brain is high, which lacks an antioxidative protection mechanism. Recently, it has been found that polyphenols p...

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Detalles Bibliográficos
Autores principales: Ye, Qinyong, Ye, Linfeng, Xu, Xianjie, Huang, Bixia, Zhang, Xiaodong, Zhu, Yuangui, Chen, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404027/
https://www.ncbi.nlm.nih.gov/pubmed/22742579
http://dx.doi.org/10.1186/1472-6882-12-82