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Structure and Dynamics of Amyloid-β Segmental Polymorphisms

It is believed that amyloid-beta (Aβ) aggregates play a role in the pathogenesis of Alzheimer’s disease. Aβ molecules form β-sheet structures with multiple interaction sites. This polymorphism gives rise to differences in morphology, physico-chemical property and level of cellular toxicity. We have...

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Detalles Bibliográficos
Autores principales: Berhanu, Workalemahu M., Hansmann, Ulrich H. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404032/
https://www.ncbi.nlm.nih.gov/pubmed/22911797
http://dx.doi.org/10.1371/journal.pone.0041479

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