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Whole Transcriptome Analysis of the Effects of Type I Diabetes on Mouse Oocytes

In mouse ovarian follicles, granulosa cells but not oocytes take up glucose to provide the oocyte with nourishments for energy metabolism. Diabetes-induced hyperglycemia or glucose absorption inefficiency consistently causes granulosa cell apoptosis and further exerts a series of negative impacts on...

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Detalles Bibliográficos
Autores principales: Ma, Jun-Yu, Li, Mo, Ge, Zhao-Jia, Luo, Yibo, Ou, Xiang-Hong, Song, Shuhui, Tian, Dongmei, Yang, Jin, Zhang, Bing, Ou-Yang, Ying-Chun, Hou, Yi, Liu, Zhonghua, Schatten, Heide, Sun, Qing-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404043/
https://www.ncbi.nlm.nih.gov/pubmed/22911868
http://dx.doi.org/10.1371/journal.pone.0041981