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Osteomimicry of Mammary Adenocarcinoma Cells In Vitro; Increased Expression of Bone Matrix Proteins and Proliferation within a 3D Collagen Environment

Bone is the most common site of metastasis for breast cancer, however the reasons for this remain unclear. We hypothesise that under certain conditions mammary cells possess osteomimetic capabilities that may allow them to adapt to, and flourish within, the bone microenvironment. Mammary cells are k...

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Detalles Bibliográficos
Autores principales: Cox, Rachel F., Jenkinson, Allan, Pohl, Kerstin, O’Brien, Fergal J., Morgan, Maria P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404045/
https://www.ncbi.nlm.nih.gov/pubmed/22911843
http://dx.doi.org/10.1371/journal.pone.0041679