A Molecular Switch Driving Inactivation in the Cardiac K(+) Channel hERG

K(+) channels control transmembrane action potentials by gating open or closed in response to external stimuli. Inactivation gating, involving a conformational change at the K(+) selectivity filter, has recently been recognized as a major K(+) channel regulatory mechanism. In the K(+) channel hERG,...

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Detalles Bibliográficos
Autores principales: Köpfer, David A., Hahn, Ulrike, Ohmert, Iris, Vriend, Gert, Pongs, Olaf, de Groot, Bert L., Zachariae, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404103/
https://www.ncbi.nlm.nih.gov/pubmed/22848423
http://dx.doi.org/10.1371/journal.pone.0041023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404103/
https://www.ncbi.nlm.nih.gov/pubmed/22848423
http://dx.doi.org/10.1371/journal.pone.0041023

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