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A Molecular Switch Driving Inactivation in the Cardiac K(+) Channel hERG
K(+) channels control transmembrane action potentials by gating open or closed in response to external stimuli. Inactivation gating, involving a conformational change at the K(+) selectivity filter, has recently been recognized as a major K(+) channel regulatory mechanism. In the K(+) channel hERG,...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404103/ https://www.ncbi.nlm.nih.gov/pubmed/22848423 http://dx.doi.org/10.1371/journal.pone.0041023 |