Ascorbic Acid Has Superior Ex Vivo Antiproliferative, Cell Death-Inducing and Immunomodulatory Effects over IFN-α in HTLV-1-Associated Myelopathy

BACKGROUND: Clear therapeutic guidelines for HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) are missing due to the lack of randomized double-blind controlled clinical trials. Moderate yet similar clinical benefit has been demonstrated for IFN-α and high-dose ascorbic acid (AA) m...

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Detalles Bibliográficos
Autores principales: Moens, Britta, Decanine, Daniele, Menezes, Soraya Maria, Khouri, Ricardo, Silva-Santos, Gilvanéia, Lopez, Giovanni, Alvarez, Carolina, Talledo, Michael, Gotuzzo, Eduardo, de Almeida Kruschewsky, Ramon, Galvão-Castro, Bernardo, Vandamme, Anne-Mieke, Van Weyenbergh, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404116/
https://www.ncbi.nlm.nih.gov/pubmed/22848768
http://dx.doi.org/10.1371/journal.pntd.0001729

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404116/
https://www.ncbi.nlm.nih.gov/pubmed/22848768
http://dx.doi.org/10.1371/journal.pntd.0001729

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