Leishmania major Infection in Humanized Mice Induces Systemic Infection and Provokes a Nonprotective Human Immune Response

BACKGROUND: Leishmania (L.) species are the causative agent of leishmaniasis. Due to the lack of efficient vaccine candidates, drug therapies are the only option to deal with cutaneous leishmaniasis. Unfortunately, chemotherapeutic interventions show high toxicity in addition to an increased risk of...

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Detalles Bibliográficos
Autores principales: Wege, Anja Kathrin, Florian, Christian, Ernst, Wolfgang, Zimara, Nicole, Schleicher, Ulrike, Hanses, Frank, Schmid, Maximilian, Ritter, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404120/
https://www.ncbi.nlm.nih.gov/pubmed/22848771
http://dx.doi.org/10.1371/journal.pntd.0001741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404120/
https://www.ncbi.nlm.nih.gov/pubmed/22848771
http://dx.doi.org/10.1371/journal.pntd.0001741

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