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Leishmania major Infection in Humanized Mice Induces Systemic Infection and Provokes a Nonprotective Human Immune Response
BACKGROUND: Leishmania (L.) species are the causative agent of leishmaniasis. Due to the lack of efficient vaccine candidates, drug therapies are the only option to deal with cutaneous leishmaniasis. Unfortunately, chemotherapeutic interventions show high toxicity in addition to an increased risk of...
Autores principales: | Wege, Anja Kathrin, Florian, Christian, Ernst, Wolfgang, Zimara, Nicole, Schleicher, Ulrike, Hanses, Frank, Schmid, Maximilian, Ritter, Uwe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404120/ https://www.ncbi.nlm.nih.gov/pubmed/22848771 http://dx.doi.org/10.1371/journal.pntd.0001741 |
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