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The Bcl-2 family member BIM has multiple glaucoma-relevant functions in DBA/2J mice
Axonal insult induces retinal ganglion cell (RGC) death through a BAX-dependent process. The pro-apoptotic Bcl-2 family member BIM is known to induce BAX activation. BIM expression increased in RGCs after axonal injury and its induction was dependent on JUN. Partial and complete Bim deficiency delay...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404412/ https://www.ncbi.nlm.nih.gov/pubmed/22833783 http://dx.doi.org/10.1038/srep00530 |