Two-compartment tumor metabolism: Autophagy in the tumor microenvironment and oxidative mitochondrial metabolism (OXPHOS) in cancer cells

Previously, we proposed a new paradigm to explain the compartment-specific role of autophagy in tumor metabolism. In this model, autophagy and mitochondrial dysfunction in the tumor stroma promotes cellular catabolism, which results in the production of recycled nutrients. These chemical building bl...

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Detalles Bibliográficos
Autores principales: Salem, Ahmed F., Whitaker-Menezes, Diana, Lin, Zhao, Martinez-Outschoorn, Ubaldo E., Tanowitz, Herbert B., Al-Zoubi, Mazhar Salim, Howell, Anthony, Pestell, Richard G., Sotgia, Federica, Lisanti, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404881/
https://www.ncbi.nlm.nih.gov/pubmed/22722266
http://dx.doi.org/10.4161/cc.20920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404881/
https://www.ncbi.nlm.nih.gov/pubmed/22722266
http://dx.doi.org/10.4161/cc.20920

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