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Copper compound induces autophagy and apoptosis of glioma cells by reactive oxygen species and jnk activation
BACKGROUND: Glioblastoma multiforme (GBM) is the most aggressive of the primary brain tumors, with a grim prognosis despite intensive treatment. In the past decades, progress in research has not significantly increased overall survival rate. METHODS: The in vitro antineoplastic effect and mechanism...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404907/ https://www.ncbi.nlm.nih.gov/pubmed/22540380 http://dx.doi.org/10.1186/1471-2407-12-156 |