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Adeno-associated virus-mediated doxycycline-regulatable TRAIL expression suppresses growth of human breast carcinoma in nude mice

BACKGROUND: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) functions as a cytokine to selectively kill various cancer cells without toxicity to most normal cells. Numerous studies have demonstrated the potential use of recombinant soluble TRAIL as a cancer therapeutic agent. We have...

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Detalles Bibliográficos
Autores principales: Zheng, Liu, Weilun, Zhang, Minghong, Jiang, Yaxi, Zhang, Shilian, Liu, Yanxin, Liu, Dexian, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404920/
https://www.ncbi.nlm.nih.gov/pubmed/22530952
http://dx.doi.org/10.1186/1471-2407-12-153