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Fbxw7 regulates Notch to control specification of neural precursors for oligodendrocyte fate

BACKGROUND: In the developing vertebrate nervous system elevated levels of Notch signaling activity can block neurogenesis and promote formation of glial cells. The mechanisms that limit Notch activity to balance formation of neurons and glia from neural precursors are poorly understood. RESULTS: By...

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Detalles Bibliográficos
Autores principales: Snyder, Julia L, Kearns, Christina A, Appel, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404928/
https://www.ncbi.nlm.nih.gov/pubmed/22554084
http://dx.doi.org/10.1186/1749-8104-7-15