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Customized chemotherapy based on epidermal growth factor receptor mutation status for elderly patients with advanced non-small-cell lung cancer: a phase II trial

BACKGROUND: Elderly patients are more vulnerable to toxicity from chemotherapy. Activating epidermal growth factor receptor (EGFR) mutations in non-small-cell lung cancer (NSCLC) are associated with enhanced response to EGFR tyrosine-kinase inhibitors. We studied patients with advanced NSCLC for who...

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Detalles Bibliográficos
Autores principales: Fujita, Shiro, Katakami, Nobuyuki, Masago, Katsuhiro, Yoshioka, Hiroshige, Tomii, Keisuke, Kaneda, Toshihiko, Hirabayashi, Masataka, Kunimasa, Kei, Morizane, Toshio, Mio, Tadashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404930/
https://www.ncbi.nlm.nih.gov/pubmed/22613958
http://dx.doi.org/10.1186/1471-2407-12-185