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Inflammation Drives Dysbiosis and Bacterial Invasion in Murine Models of Ileal Crohn’s Disease

BACKGROUND AND AIMS: Understanding the interplay between genetic susceptibility, the microbiome, the environment and the immune system in Crohn’s Disease (CD) is essential for developing optimal therapeutic strategies. We sought to examine the dynamics of the relationship between inflammation, the i...

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Detalles Bibliográficos
Autores principales: Craven, Melanie, Egan, Charlotte E., Dowd, Scot E., McDonough, Sean P., Dogan, Belgin, Denkers, Eric Y., Bowman, Dwight, Scherl, Ellen J., Simpson, Kenneth W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404971/
https://www.ncbi.nlm.nih.gov/pubmed/22848538
http://dx.doi.org/10.1371/journal.pone.0041594