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LRP5 Regulates Development of Lung Microvessels and Alveoli through the Angiopoietin-Tie2 Pathway

Angiogenesis is crucial for lung development. Although there has been considerable exploration, the mechanism by which lung vascular and alveolar formation is controlled is still not completely understood. Here we show that low-density lipoprotein receptor-related protein 5 (LRP5), a component of th...

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Detalles Bibliográficos
Autores principales: Mammoto, Tadanori, Chen, Jing, Jiang, Elisabeth, Jiang, Amanda, Smith, Lois E., Ingber, Donald E., Mammoto, Akiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404972/
https://www.ncbi.nlm.nih.gov/pubmed/22848540
http://dx.doi.org/10.1371/journal.pone.0041596