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MGMT, GATA6, CD81, DR4, and CASP8 gene promoter methylation in glioblastoma

BACKGROUND: Methylation of promoter region is the major mechanism affecting gene expression in tumors. Recent methylome studies of brain tumors revealed a list of new epigenetically modified genes. Our aim was to study promoter methylation of newly identified epigenetically silenced genes together w...

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Detalles Bibliográficos
Autores principales: Skiriute, Daina, Vaitkiene, Paulina, Saferis, Viktoras, Asmoniene, Virginija, Skauminas, Kestutis, Deltuva, Vytenis Pranas, Tamasauskas, Arimantas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404983/
https://www.ncbi.nlm.nih.gov/pubmed/22672670
http://dx.doi.org/10.1186/1471-2407-12-218