Effects of Dimethyl Sulfoxide in Cholesterol-Containing Lipid Membranes: A Comparative Study of Experiments In Silico and with Cells

Dimethyl sulfoxide (DMSO) has been known to enhance cell membrane permeability of drugs or DNA. Molecular dynamics (MD) simulations with single-component lipid bilayers predicted the existence of three regimes of action of DMSO: membrane loosening, pore formation and bilayer collapse. We show here t...

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Detalles Bibliográficos
Autores principales: de Ménorval, Marie-Amélie, Mir, Lluis M., Fernández, M. Laura, Reigada, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404987/
https://www.ncbi.nlm.nih.gov/pubmed/22848583
http://dx.doi.org/10.1371/journal.pone.0041733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404987/
https://www.ncbi.nlm.nih.gov/pubmed/22848583
http://dx.doi.org/10.1371/journal.pone.0041733

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