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The Potential of Avian H1N1 Influenza A Viruses to Replicate and Cause Disease in Mammalian Models
H1N1 viruses in which all gene segments are of avian origin are the most frequent cause of influenza pandemics in humans; therefore, we examined the disease-causing potential of 31 avian H1N1 isolates of American lineage in DBA/2J mice. Thirty of 31 isolates were very virulent, causing respiratory t...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404991/ https://www.ncbi.nlm.nih.gov/pubmed/22848544 http://dx.doi.org/10.1371/journal.pone.0041609 |