The Odyssey of Hsp60 from Tumor Cells to Other Destinations Includes Plasma Membrane-Associated Stages and Golgi and Exosomal Protein-Trafficking Modalities

BACKGROUND: In a previous work we showed for the first time that human tumor cells secrete Hsp60 via exosomes, which are considered immunologically active microvesicles involved in tumor progression. This finding raised questions concerning the route followed by Hsp60 to reach the exosomes, its loca...

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Detalles Bibliográficos
Autores principales: Campanella, Claudia, Bucchieri, Fabio, Merendino, Anna M., Fucarino, Alberto, Burgio, Giosalba, Corona, Davide F. V., Barbieri, Giovanna, David, Sabrina, Farina, Felicia, Zummo, Giovanni, de Macario, Everly Conway, Macario, Alberto J. L., Cappello, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405006/
https://www.ncbi.nlm.nih.gov/pubmed/22848686
http://dx.doi.org/10.1371/journal.pone.0042008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405006/
https://www.ncbi.nlm.nih.gov/pubmed/22848686
http://dx.doi.org/10.1371/journal.pone.0042008

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