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Identification of the Substrate Recognition and Transport Pathway in a Eukaryotic Member of the Nucleobase-Ascorbate Transporter (NAT) Family

Using the crystal structure of the uracil transporter UraA of Escherichia coli, we constructed a 3D model of the Aspergillus nidulans uric acid-xanthine/H(+) symporter UapA, which is a prototype member of the Nucleobase-Ascorbate Transporter (NAT) family. The model consists of 14 transmembrane segme...

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Detalles Bibliográficos
Autores principales: Kosti, Vasiliki, Lambrinidis, George, Myrianthopoulos, Vassilios, Diallinas, George, Mikros, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405029/
https://www.ncbi.nlm.nih.gov/pubmed/22848666
http://dx.doi.org/10.1371/journal.pone.0041939