Local Loperamide Injection Reduces Mechanosensitivity of Rat Cutaneous, Nociceptive C-Fibers

Loperamide reverses signs of mechanical hypersensitivity in an animal model of neuropathic pain suggesting that peripheral opioid receptors may be suitable targets for the treatment of neuropathic pain. Since little is known about loperamide effects on the responsiveness of primary afferent nerve fi...

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Detalles Bibliográficos
Autores principales: Ringkamp, Matthias, Tal, Michael, Hartke, Timothy V., Wooten, Matthew, McKelvy, Alvin, Turnquist, Brian P., Guan, Yun, Meyer, Richard A., Raja, Srinivasa N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405035/
https://www.ncbi.nlm.nih.gov/pubmed/22848720
http://dx.doi.org/10.1371/journal.pone.0042105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405035/
https://www.ncbi.nlm.nih.gov/pubmed/22848720
http://dx.doi.org/10.1371/journal.pone.0042105

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