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Helminth Antigens Enable CpG-Activated Dendritic Cells to Inhibit the Symptoms of Collagen-induced Arthritis through Foxp3+ Regulatory T Cells

Dendritic cells (DC) have the potential to control the outcome of autoimmunity by modulating the immune response. In this study, we tested the ability of Fasciola hepatica total extract (TE) to induce tolerogenic properties in CpG-ODN (CpG) maturated DC, to then evaluate the therapeutic potential of...

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Detalles Bibliográficos
Autores principales: Carranza, Franco, Falcón, Cristian Roberto, Nuñez, Nicolás, Knubel, Carolina, Correa, Silvia Graciela, Bianco, Ismael, Maccioni, Mariana, Fretes, Ricardo, Triquell, María Fernanda, Motrán, Claudia Cristina, Cervi, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405066/
https://www.ncbi.nlm.nih.gov/pubmed/22848374
http://dx.doi.org/10.1371/journal.pone.0040356