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Sensitization of Human Pancreatic Cancer Cells Harboring Mutated K-ras to Apoptosis
Pancreatic cancer is a devastating human malignancy and gain of functional mutations in K-ras oncogene is observed in 75%–90% of the patients. Studies have shown that oncogenic ras is not only able to promote cell growth or survival, but also apoptosis, depending upon circumstances. Using pancreatic...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405084/ https://www.ncbi.nlm.nih.gov/pubmed/22848379 http://dx.doi.org/10.1371/journal.pone.0040435 |