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PKC-Dependent Human Monocyte Adhesion Requires AMPK and Syk Activation

PKC plays a pivotal role in mediating monocyte adhesion; however, the underlying mechanisms of PKC-mediated cell adhesion are still unclear. In this study, we elucidated the signaling network of phorbol ester PMA-stimulated human monocyte adhesion. Our results with pharmacological inhibitors suggest...

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Detalles Bibliográficos
Autores principales: Chang, Mei-Ying, Huang, Duen-Yi, Ho, Feng-Ming, Huang, Kuo-Chin, Lin, Wan-Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405105/
https://www.ncbi.nlm.nih.gov/pubmed/22848421
http://dx.doi.org/10.1371/journal.pone.0040999