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Neurogranin Targets Calmodulin and Lowers the Threshold for the Induction of Long-Term Potentiation
Calcium entry and the subsequent activation of CaMKII trigger synaptic plasticity in many brain regions. The induction of long-term potentiation (LTP) in the CA1 region of the hippocampus requires a relatively high amount of calcium-calmodulin. This requirement is usually explained, based on in vitr...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405117/ https://www.ncbi.nlm.nih.gov/pubmed/22848456 http://dx.doi.org/10.1371/journal.pone.0041275 |