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Fibroblast EXT1-Levels Influence Tumor Cell Proliferation and Migration in Composite Spheroids
BACKGROUND: Stromal fibroblasts are important determinants of tumor cell behavior. They act to condition the tumor microenvironment, influence tumor growth, support tumor angiogenesis and affect tumor metastasis. Heparan sulfate proteoglycans, present both on tumor and stromal cells, interact with a...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405129/ https://www.ncbi.nlm.nih.gov/pubmed/22848466 http://dx.doi.org/10.1371/journal.pone.0041334 |