Soft fibrin gels promote selection and growth of tumourigenic cells

The identification of stem-cell-like cancer cells through conventional methods that depend on stem-cell markers is often unreliable. We developed a mechanical method of selecting tumourigenic cells by culturing single cancer cells in fibrin matrices of ~100 Pa in stiffness. When cultured within thes...

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Detalles Bibliográficos
Autores principales: Liu, Jing, Tan, Youhua, Zhang, Huafeng, Zhang, Yi, Xu, Pingwei, Chen, Junwei, Poh, Yeh-Chuin, Tang, Ke, Wang, Ning, Huang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405191/
https://www.ncbi.nlm.nih.gov/pubmed/22751180
http://dx.doi.org/10.1038/nmat3361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405191/
https://www.ncbi.nlm.nih.gov/pubmed/22751180
http://dx.doi.org/10.1038/nmat3361

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